Genetic variant annotation and effect prediction toolbox.
Latest version 4.0 E (2014-09-13)
Requires Java 1.7
Genetic variant annotation and effect prediction toolbox. It annotates and predicts the effects of variants on genes (such as amino acid changes).
Major improvements and support for standards:
SnpSift helps filtering and manipulating genomic annotated files (VCF). Once you annotated your files using SnpEff, you can use SnpSift to help you filter large genomic datasets in order to find the most significant variants
If you are using SnpEff or SnpSift in an research or academic environment, please cite our papers.
Users of SnpEff include most major research an academic institutions, as well as pharmaceutical companies and clinical sequencing projects.