SnpEff

Genetic variant annotation and effect prediction toolbox.

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Latest version 3.2a (2013-04-11)

SnpEff

Genetic variant annotation and effect prediction toolbox. It annotates and predicts the effects of variants on genes (such as amino acid changes).
SnpEff currently supports over 2,500 genomes.

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Version 3.2a

Several improvement and bug fixes.

  • GATK compatibile (-o gatk)
  • Cancer variants analysis
  • HGSV notations support
  • Loss of function tag
  • Nonsense-mediated decay effect
  • SnpSift: PhastCons annotations

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SnpSift

SnpSift helps filtering and manipulating genomic annotated files (VCF). Once you annotated your files using SnpEff, you can use SnpSift to help you filter large genomic datasets in order to find the most significant variants

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Paper & Citing

If you are using SnpEff or SnpSift in an research or academic environment, please cite our papers.

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Who uses SnpEff?

Users of SnpEff include most mayor research an academic institutions, as well as pharmaceutical companies and clinical sequencing projects.

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Galaxy & GATK

SnpEff is integrated with other tools commonly used in sequencing data analysis pipelines. Most notably Galaxy and GATK projects support SnpEff.

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